Napoli vs Inter prediction, H2H and probable lineups, October 25, 2025

By Author On Oct 25, 2025

It’s that time again — Napoli and Inter go head-to-head in a fiery Serie A matchup that could shake up the title race. Both sides are pushing hard this season, and this weekend’s game at the Stadio Diego Armando Maradona promises drama, goals, and maybe even a few nerves.

Form Guide

Napoli have been pretty solid lately but not quite flawless. They’ve shown glimpses of last season’s spark, with their attack clicking again and Victor Osimhen looking dangerous up front. However, a couple of shaky defensive moments have cost them easy points recently.

Inter, on the other hand, are flying. Simone Inzaghi’s men are ruthless on the break and clinical in front of goal. Lautaro Martínez has been on fire, and the midfield duo of Barella and Calhanoglu are running the show. The Nerazzurri come into this one unbeaten in their last six and full of confidence.

Head-to-Head Record

These two have a long history of tight, fiery encounters. Inter have had the upper hand in recent meetings, winning three of their last five clashes. Napoli did snatch a win last season, though, so they’ll fancy their chances at home. Expect intensity — it’s rarely dull when these two meet.

Team News

Napoli boss Rudi Garcia has most of his main men available, though midfielder André-Frank Zambo Anguissa remains a doubt after a minor knock. Osimhen should start up top, with Kvaratskhelia and Politano offering width.

Inter look strong too, but Marcus Thuram is a late fitness concern. If he misses out, Arnautović might get a rare start alongside Lautaro. The defense — led by Acerbi and Bastoni — remains rock solid.

Predicted Lineups

Napoli (4-3-3): Meret; Di Lorenzo, Rrahmani, Natan, Olivera; Lobotka, Zielinski, Cajuste; Politano, Osimhen, Kvaratskhelia.

Inter (3-5-2): Sommer; Darmian, Acerbi, Bastoni; Dumfries, Barella, Calhanoglu, Mkhitaryan, Dimarco; Lautaro, Thuram (or Arnautović).

Players to Watch

Match Prediction

This one’s tough to call. Napoli at home are always dangerous, but Inter’s form and tactical discipline might just give them the edge. Expect goals at both ends and plenty of action.

Prediction: Napoli 1–2 Inter

Betting Tips

Both Teams to Score: Yes
Over 2.5 Goals: Likely
Anytime Scorer: Lautaro Martínez
Correct Score Bet: 1–2 Inter

Inter look slightly sharper overall, but it wouldn’t be shocking if Napoli steal a draw late on.

Wrap-Up

This Napoli vs Inter clash has everything — form, fire, and title race implications. Napoli will want revenge and home pride, while Inter will be eyeing another big win to stay on top. Whatever happens, fans are in for a cracking Serie A night.