As Napoli prepare to face Pisa on September 22, 2025, both teams enter this clash seeking momentum in their respective campaigns. This article provides a comprehensive Napoli vs Pisa prediction, analyzing their head-to-head (H2H) record, current form, lineup news, and key betting insights.
Napoli vs Pisa: Recent Form and Match Context
Napoli, a top contender in Serie A, have consistently shown strong performances at home. Their dynamic attacking style, led by key players, puts them in a favorable position against Pisa, who currently compete in Serie B but have proven resilient on their travels.
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Napoli’s recent form: Unbeaten in their last five Serie A matches, showcasing solid defense and lethal counterattacks.
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Pisa’s recent form: Mixed results with a couple of draws and wins, but their away form reveals some vulnerabilities.
This match presents a classic scenario where high-tier quality meets determined underdog spirit, shaping an intriguing contest.
Head-to-Head (H2H) Record
The historical encounters between Napoli and Pisa are limited due to their different league status, but previous cup meetings have favored Napoli:
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Napoli have won 3 of the last 4 meetings.
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Pisa’s only victory came in a tightly contested Italian Cup tie.
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Goal difference heavily favors Napoli, with a +5 margin in these matches.
This H2H overview indicates Napoli’s dominance, especially in home fixtures.
Expected Lineups and Key Players
Napoli probable lineup:
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Goalkeeper: Alex Meret
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Defense: Di Lorenzo, Kim Min-jae, Rrahmani, Mario Rui
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Midfield: Anguissa, Lobotka, Zieliński
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Attack: Kvaratskhelia, Osimhen, Politano
Injury updates confirm all key Napoli players are fit and expected to start, maintaining their preferred tactical setup.
Pisa probable lineup:
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Goalkeeper: Gori
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Defense: Masi, Buonaiuto, Marconi, Zommers
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Midfield: Roberti, Masucci, Masetti
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Attack: Kouame, Galazzi, Pettinari
Pisa rely heavily on cohesive teamwork and set-piece opportunities to challenge stronger sides.
Napoli vs Pisa Prediction and Betting Tips
Considering Napoli’s home advantage, consistent form, and superior squad depth, Napoli is strongly favored to secure a win in this match. Pisa’s resilience may limit the goal margin, but an upset appears unlikely.
Key Prediction Points:
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Expected scoreline: Napoli 3 – 1 Pisa
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Napoli to Keep a Clean Sheet: Unlikely due to Pisa’s attacking threats
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Over/Under Goals: Expect over 2.5 goals given Napoli’s offensive firepower
Betting Tips:
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Back Napoli to win with a handicap (-1).
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Consider the “Both Teams to Score” market as viable.
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Look for value odds on Napoli’s leading scorer to find the net.
Conclusion
The Napoli vs Pisa showdown on September 22 promises an engaging contest with a clear edge for Napoli, bolstered by their H2H record, lineup strength, and superior recent form. This prediction favors a confident home victory supported by incisive attacking play and organized defense.
